IN SILICO ANALYSIS REVEALED FIVE NOVEL HIGH-RISK SINGLE-NUCLEOTIDE POLYMORPHISMS (RS200384291, RS201163886, RS193141883, RS201139487, AND RS201723157) IN ELANE GENE CAUSING AUTOSOMAL DOMINANT SEVERE CONGENITAL NEUTROPENIA 1 AND CYCLIC HEMATOPOIESIS

Single-nucleotide polymorphisms in the ELANE (Elastase, Neutrophil Expressed) gene are associated with severe congenital neutropenia, while the ELANE gene provides instructions for making a protein called neutrophil elastase.We identified disease susceptibility single-nucleotide polymorphisms (SNPs) in the ELANE gene using several computational too

Orientation: The focus of the study was to investigate the predictive relationship between the work engagement-burnout continuum and turnover intentions.Research purpose: The Turkey Tail main purpose of the study was to determine whether work engagement, burnout, organisational citizenship behaviour (OCB) and work alienation are predictors of turno

It is very important to be able to deduce an unknown conclusion from one or several known premises when solving a logical inference.The existing inference methods or models have certain logical inference abilities.However, because of the diversity of the forms of problems and the complexity of the derivation process, the scope of Cargo Trousers app

Objetive.To describe and discuss preliminarily the informational flow related to the processes of information and knowledge management involved in the elaboration of models for granting GAN quotas of scholarships from institutional development programs of CAPES.Method.The procedures involved in the management of information and knowledge related to